Why, yes! I do kind of live here
If you've used a different address on your résumé to tailor it to where the job is based, don't lie about it when it comes up in the interview. If your potential employer asks you where you live, tell them where you currently live, but let them know that you're willing to move for the job. The problem with this lie is you may have several rounds of interviews and you'll have to keep flying back and forth for them. If they think you live in the city, they'll probably give you short notice for interviews and those last-minute flights can be really expensive.
I make so much more than my real salary
If your interviewer asks you how much you made at your last job, you may think it's a white lie to fudge the numbers a little. However, some employers ask for a copy of your W2, so you may want to be cautious about giving a fake amount because it can be construed as unethical. If you don't want to cough up your previous salary, let it be known that you don't think it has any bearing on this new job and cite the typical industry number. If you're pushed to give your previous income, tell them you won't consider an offer below $XX. This is a gray area that many have different opinions on — some like Bargaineering founder Jim Wang don't think that there's anything wrong with a little inflation, while others vehemently disagree.
That's totally my GPA
If you think that inflating your grade point average will get you the job, you may want to reconsider. Some companies request a copy of your transcript or verification with the school, especially those with job positions that require a minimum GPA.
No, I didn't get fired at my last job
Given the bad economy, there are plenty of people that have been laid off so don't be afraid to let the interviewer know. Try not to go into the details, especially if you harbor resentment, and let her know what happened and what you learned from the experience.
Remember, the general rule of thumb is to be honest during your interview. It's different for everyone, but if you get asked uncomfortable questions, there's always a polite way of refusing to answer.